The vampire weapon can also infect while to become a vampire in Skyrim as well. There are high chances of getting infected with the spell of Vampiric drain if a vampire uses it on you. This strange virus takes three days to infect and slowly turn the host into a vampire. If you intend to become a vampire in Skyrim, you need to contract the SanguinareVampiris virus. how to become a vampire in skyrim xbox 360 Become a Vampire: SanguinareVampiris virus With Dawnguard DLC expansion, the role of vampires in Skyrim will make gradual progress in the upcoming sections. These vampires with unique physical appearance have glowing red eyes, pointed teeth, and a whitish complexion. Anyone can become a vampire in the Skyrim game as they are widespread throughout the world. Vampires in Skyrim are superhuman with extreme paranormal abilities. Becoming a Vampire is the primary thought in the Skyrim world with undead beings that hate sunlight and feed on blood.